朱 进 博士 副教授 -------------------------------------------------------------------------------- 电话: 021-64252584 -------------------------------------------------------------------------------- 传真: 021-64252584 -------------------------------------------------------------------------------- E-mail: jinz@ecust.edu.cn -------------------------------------------------------------------------------- 个人简介 -------------------------------------------------------------------------------- 2000.9-2003.7 沈阳药科大学,理学学士/理学硕士 2003.7-2006.12 华中科技大学同济威廉希尔,讲师 2007.3-2009.6 英国威廉希尔公司,医学博士 2009.6-至今 英国威廉希尔公司制药工程系,讲师,副教授 研究方向 -------------------------------------------------------------------------------- 1. 药物设计与合成 2. 有机小分子催化反应 以第一或通讯作者身份发表的代表性论著 -------------------------------------------------------------------------------- (1) The ethylene bis-dithiocarbamate fungicide Mancozeb activates voltage-gated KCNQ2 potassium channel. Toxicol. Lett. 2013, 219, 211−217. (2) Design and synthesis of small molecular dual inhibitor of falcipain-2 and dihydrofolate reductase as antimalarial agent. Bioorg. Med. Chem. Lett. 2012, 22, 958−962. (3) Direct oxidative conversion of 3-aryl propionaldehydes to 3-aryl acroleins promoted by SOMO catalysis.Tetrahedron Lett. 2012, 53, 1207−1209. (4) 1-(2,6-Dibenzyloxybenzoyl)-3-(9H-fluoren-9-yl)-urea: A novel cyclophilin A allosteric activator. Biochem. Biophy. Res. Commun. 2012, 425, 938−943. (5) 2-(3,4-Dihydro-4-oxothieno[2,3-d]pyrimidin-2-ylthio)acetamides as a new class of falcipain-2 inhibitors. 3. design, synthesis and biological evaluation. Molecules. 2009, 14, 785−797. (6) Refinement and 3D-QSAR studies of inhibitors of cyclophilin A containing amide linker. QSAR Comb. Sci. 2009, 28, 183−193. (7) A direct amine-Palladium acetate cocatalyzed saegusa oxidation reaction of unmodified aldehydes to α,β-unsaturated aldehydes. Adv. Synth. Catal. 2009, 351, 1229−1232. |